???, ??????? ??? ???? ?????????????? ???????? ??? ???????????? ?????????? ????????? ????????? ?????? ??????? ??????, ????????????? ?????? ??????? Changing ??????????????????????????????? ??????? ?? ???????????? ??????. ?? a small 2017 examine, ighty one Gentlemen ??? postmenopausal Ladies ???? ?????????????? ??? 50 ??????????? ???????????????????